in the mid 2000s, the actress returned to television with roles in “ally mcbeal” and “malcolm in the middle,” while also appearing in films such as 2004’s “tiger cruise” and 2005’s “ice princess.”
in 2006, panettiere shot to international stardom, landing the lead role of claire bennet, a high school cheerleader with self-healing powers, in the nbc show “heroes.”
after “heroes” concluded in 2010, panettiere starred as kirby reed in 2011’s “scream 4”, a role she later reprised in “scream 6” in 2023.
between 2012 and 2018, panettiere portrayed juliette barnes, opposite connie britton’s rayna jaymes in six seasons of abc’s musical drama “nashville.”
her most recent credits include “amber alert” in 2024 and “a breed apart” in 2025. her final film role, “sleepwalker,” will be released in theatres in january 2027, people reported.
us actress hayden panettiere arrives for the “emmy nominees night” event hosted by the hollywood reporter and sag-aftra in west hollywood, california, on september 10, 2022.
michael tran
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afp via getty images
panettiere had personal struggles
in 2014, panettiere welcomed a daughter, kaya, with her then-fiance, ukrainian champion heavyweight boxer wladimir klitschko. she and klitschko raised their daughter for the first four years of her life, but in 2018, panettiere gave full custody to klitschko.
panettiere recently appeared on jay shetty’s “on purpose” podcast, where she denied that she “gave away” kaya to klitschko, stating the decision to give up full custody was “heartbreaking.”
the actress said at the time of the custody change she was seeking treatment for alcoholism, substance abuse and postpartum depression, per
people.
“i was on top of the world, and i ruined it,” she told
people in 2022, highlighting that she spent years battling addiction and postpartum depression. “i’d think i hit rock bottom, but then there’s that trap door that opens.”
in february 2023, her younger brother, actor jensen panettiere, died of aortic valve complications at age 28, per
the hollywood reporter.